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The TRIUMPH-4 trial revealed a notable incidence of dysesthesia, an abnormal sensation affecting touch perception that can cause numbness, tingling, or unusual skin sensitivity
(Off-label use is when doctors prescribe a drug for a purpose other than what its approved for.) Researchers compared changes in weight between people who took Trulicity and those who took other diabetes drugs
The problem was compounded (no pun intended) by the lack of CMS coverage for GLP-1s for weight loss as well as patchy private insurance
J Ethnopharmacol (1990) 30:28194
