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Bill Hartman discusses news that the maker of Ozempic is studying its effects on alcohol consumption, as well as the health benefits associated with a plant-based diet.

Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node GLP-1 has direct chronotropic effects on the heart mediated by GLP-1 receptors in pacemaker cells of the sinus node, inducing changes in action potential morphology

However, the insulinotropic effect of incretins is diminished in type 2 diabetic patients, due in part to reduced expression of incretin receptors as a consequence of glucotoxicity