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Tirzepatide acts on both GLP-1 and GIP receptors, while semaglutide acts on GLP-1 alone, which partially explains the dosing differences

#Diabetes #NHS #HealthInnovation #NICEGuidelines #Type2Diabetes #SGLT2 #GLP1 Excuse the typos That's all good, these medications try to tackle the problem downstream - what is more effective is attacking it up stream - by changing what is actually enterring the body via diet

Well start with the core problem: TRT suppresses LH and FSH , which over time can reduce intratesticular testosterone, sperm output, and testicular fullness

Tirzepatide (a dual GLP-1 and GIP receptor agonist) has a distinct chemical structure and may be better tolerated by people who react to semaglutide alone