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Description
The binding affinity of lixisenatide to GLP-1R is fourfold higher than native GLP-1 (17)
Over time, the pancreas loses its ability to function properly, which can have wide-reaching effects on your health
Semaglutide (Ozempic, Wegovy) targets one receptor: GLP-1
One possible explanation is that the anti-inflammatory and neuroimmune effects of GLP-1 receptor activation may occur at lower levels of receptor engagement than the metabolic effects (like weight loss or appetite suppression)
