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Activation of NTS GLP-1R neurons induced nonaversive satiety, likely via projections to the PVH, and this circuit was preferentially activated by nutrients rather than non-nutritive aversive stimuli (123)

Ces mdicaments imitent un peptide naturel produit par lorganisme appel GLP-1, une molcule qui joue un rle cl dans la rgulation de lapptit et du mtabolisme, mais qui est dgrade en quelques minutes dans lorganisme par certaines enzymes

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Nonetheless, potential benefits of GLP-1RAs on aspects of NUD may be observed in some persons taking these agents for on-label indications (e.g., obesity, T2DM)