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PlexusDx patients seeking personalized medication selection can add the Precision Peptide Genetic Test ($99 after first month) to identify genetic variants in GIPR, GLP1R, FTO, and MC4R pathwaysinsights that predict individual response to GLP-1/GIP therapies

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While the agreements do not address prices charged to employer health plan sponsors and covered plan members, as drug manufacturers have begun making GLP-1 medications available well below list price through their own direct-to-consumer programs, the major PBMs say they have generally been able to negotiate discounts and rebates for group health plans that effectively bring net costs for these drugs close to DTC costs

However, when insulin sensitivity is lowknown as insulin resistanceglucose builds up in the bloodstream, increasing the risk of type 2 diabetes, obesity, and other metabolic disorders