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During exercise, it is thought to act in a hormone-like manner to stimulate energy mobilization, leading to increased body temperature and highlighting its metabolic functions (102)
Consequently, the inclusion of mannitol effectively adjusted the particle size of semaglutide, and semaglutide-loaded DPI showed improved lung delivery efficiency
Interestingly, GLP-1 signaling in the hippocampus has been described to play a direct and crucial role in regulating learning and memory, independent of motor, stress, or nociceptive impacts

Peptide-HLA complexes can then be trafficked to and presented on the cell surface
