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Do not double up to make up for missed doses, as this increases side effect risk without improving outcomes

More than one-half of individuals with severe mental illnesses are obese or overweight, 1 resulting from multiple factors that may include psychiatric symptoms (eg, anergia and hyperphagia), poor dietary choices, sedentary lifestyle, underlying inflammatory processes, medical comorbidities, and iatrogenic consequences of certain medications

Spironolactone: Uses, Side Effects, a Comprehensive Guide Table of Contents Spironolactone, now a medication with wide applications, was originally introduced as a diuretic (a medicine that helps the body expel excess fluid)