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Description
Five clinical trials (SURPASS 1-5 trials) conducted in patients with T2DM showed that tirzepatide at 5-15 mg per week could reduce body weight (5.4-11.7kg), which was never seen with a single drug (129)

Nagashima M, Watanabe T, Terasaki M, et al

10.3390/cells11162587 [DOI] [PMC free article] [PubMed] [Google Scholar] 46.Ben Nasr M, et al

SURMOUNT-1: This study began in late 2019 and focused on adults with obesity or overweight who did not have diabetes