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The life expectancy of people with T2D is reduced due to increased mortality from cardiovascular disease (CVD)
Dror and colleagues applied an epigenetic dosage index based on cumulative chromatin accessibility to classify -cells into two groups (Fontcuberta-PiSunyer et al., 2023)
That may sound like a dramatic prediction, but it is the conclusion I reached after reviewing a document we recently uncovered (January 12th, 2026) regulatory filing submitted by Novo Nordisk to the U.S
These findings suggest that a decrease in NAD + levels is involved in the pathogenesis of age- and obesity-related diseases in humans and rodents
