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Understanding why fatigue occurs and how to manage it effectively helps patients continue treatment safely while maintaining quality of life

Clinical trials showed patients losing 15% or more of body weight over time
Spectrochim Acta A 313:124159

Notably, in vitro findings involving intestinal absorption of P-gp substrates have been performed using Caco-2 monolayers, although these cells have variable P-gp expression based on the culture conditions (61) and it is indicated that they overexpress P-gp (62)
