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12 Administration in combination with insulin In general, when semaglutide is administered in combination with basal insulin, it is recommended that a reduction in the dose of basal insulin should be considered to reduce the risk of hypoglycemia

The clock excludes clock stops periods where the review is paused while the sponsor responds to Day 120 or Day 180 questions

In these patients, treatment with semaglutide may offer several advantages over conventional treatment for psoriasis, including monoclonal antibodies, due to lower cost and better tolerability

Resting heart rate (RHR) is the number of times your heart beats per minute when you are at complete rest typically measured first thing in the morning before any physical activity