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Cardiovasc Drugs Ther 31:119132 Yoshikawa M, Suzumura A, Ito A, Tamaru T, Takayanagi T (2002) Effect of phosphodiesterase inhibitors on nitric oxide production by glial cells

Currently, the ADA does not include tirzepatide as part of their agents with cardiorenal benefit [38]

GLP-1RAs also have beneficial effects on pain-related behaviors

Originally approved to treat diabetes, these GLP-1 agonists have since made headlines not just for their ability to manage obesity but to also positively influence a host of other conditions, from cardiovascular risk and fatty liver disease to neurogenerative diseases