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Abstract Purpose of Review The pharmacologic management of type 2 diabetes prioritises sodium-glucose cotransporter 2 (SGLT-2) inhibitors or glucagon-like peptide 1 (GLP-1) receptor agonists for their demonstrated cardiovascular benefits in individuals with atherosclerotic cardiovascular disease or multiple cardiovascular risk factors, chronic kidney disease, and heart failure
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Toronto-based Vimy Pharma plans to produce a made in generic version of Ozempic a move that could make weight control and diabetes treatments (two key cost drivers for benefit plans) much more affordable and accessible

doi: 10.1056/NEJMoa2301972

In addition to its effects on insulin and glucagon, GLP-1RAs work on the brain for an anorexigenic effect by promoting feelings of satiety and modulating energy homeostasis
