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This model has become a standard for modelling joint disruption in inflammatory OA in rodents
Clinical implication: Beyond glycemic control and weight loss, GLP-1 may directly influence reproductive function and fertility
Critical Appraisal of CVOTs and Evidence Gaps While the collective evidence from the CVOTs outlined in Table 1 is compelling, a critical appraisal reveals important heterogeneity and outstanding questions that are crucial for clinical interpretation [62]
The potential for oral retatrutide is less certain given the compound larger molecular size and more complex receptor binding requirements
