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Its not a substitute for statins if you need strong LDL-lowering, but it can be a very useful tool in a broader plan for heart and metabolic health

Studies suggest that patients on GLP-1 RAs may face altered gastric motility, contributing to a delay in gastric emptying that could increase the risk of aspiration, even when fasting guidelines are followed (Joshi et al

Liraglutide has shown significant weight loss compared with placebo with the majority of participants achieving more than 5% total body weight loss during the follow up period and 33% (vs 10%) achieving 10% total body weight loss or greater

Future clinical trials should refine the investigation of the direct analgesic properties of GLP-1RAs in osteoarthritis, differentiating these from the benefits linked to weight reduction, to better evaluate their clinical utility in managing osteoarthritis-related pain