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Description
When compared head-to-head with semaglutide in the SURPASS 2 trial, nausea was reported in 1722% of patients who received tirzepatide, and in 18% who received semaglutide
In contrast, the glucagon component provides its thermogenic and lipolytic benefits without clinically significant hyperglycemia
This shift is connected to the body metabolizing more fat, but it may be important in terms of safety, particularly for individuals with comorbidities
these medications are not covered for weight loss
