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Changes in leptin signaling by SOCS3 modulate fasting-induced hyperphagia and weight regain in mice
Combined with in-office treatments, patients typically notice decreased shedding first, followed by gradual regrowth over the following months
GLP-1 also has cardio- and neuroprotective effects, decreases inflammation and apoptosis, and has implications for learning and memory, reward behavior, and palatability
These are signs that the glucagon component is driving energy expenditure at a level that meaningfully contributes to the overall weight loss beyond what GLP-1 and GIP provide alone
