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The distinct half-lives and mechanisms of action suggest that independent administration schedules might be appropriate

What the FDA label actually says (and what it does not) Novo Nordisk's Wegovy prescribing information addresses weekly dosing and missed doses but does not directly answer "can I change my day?" Here is what the label says, verbatim: "Administer WEGOVY injection once weekly, on the same day each week, at any time of day, with or without meals." "The time of day and the injection site can be changed without the need for a dosage modification." For missed doses with more than 2 days until the next scheduled dose: "administer WEGOVY injection as soon as possible." For missed doses with less than 2 days until the next scheduled dose: "do not administer the WEGOVY injection dose

Increased glycosylated hemoglobin (HbA1c) and the presence of vascular complications have been associated with increased odds for sarcopenia (1.2-fold and 2.4-fold, respectively) in people with diabetes [20,23], while those with T2DM have lower muscle strength and physical performance compared to counterparts without T2DM [21]

However, large bubbles displace medication volume, which means you receive a smaller dose than intended