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Together, our results indicate that GLP-1 receptor activation enhances glutamate release at PF-PC synapses via the PKA signaling pathway, resulting in enhanced PF-PC synaptic transmission in mice in vitro

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Discover safe, effective exercise strategies that support strength, mobility, and healthy aging while on Wegovy or Zepbound.

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Mechanistically, these effects are linked to GLP-1 RA-mediated suppression of inflammatory pathways, modulation of skeletal muscle metabolism, and preservation of mitochondrial function, thereby influencing insulin resistance

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Betsy Grunch says shaming people for taking buzzy GLP-1 drugs like Mounjaro and Ozempic is like shaming people for taking blood-pressure medicine.

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