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2 Their size and amino acid composition hinder crossing cell membranes to reach intracellular targets

First, as a general rule, we focus on systems that have been well-studied, as these are the systems that have been identified and investigated for a long time, allowing us to collect substantial scientific and clinical data

(Right) GLP-1 receptor agonist (GLP-1RA) reduces cholesterol accumulation by affecting the expression of genes in the hepato-enteral circulation and cholesterol reverse transport pathway, such as farnesoid X receptor (FXR), fibroblast growth factor-15 (FGF15), fibroblast growth factor receptor 4 (FGFR4), cytochrome P450 family 7 subfamily A member 1 (Cyp7a1), proprotein convertase subtilisin/kexin type 9 (PCSK9), low-density lipoprotein receptor (LDLR), etc

The orally disintegrating tablet formulation requires specific storage conditions to preserve both the integrity of the active ingredients and the unique characteristics that allow for rapid dissolution in the oral cavity