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In fact, L-cells have also been identified in the duodenum [44] and certainly in the jejunum [15], with the respective numbers increasing aborally towards the ileum and colon/rectum [45]
It targets both the GLP-1 receptor and the GIP receptor, which is glucose-dependent insulinotropic polypeptide
Another weight loss-promoting action of Ozempic is to slow gastric emptying, or how quickly food moves from your stomach to your lower intestine

[2] The effect size is small on its own
