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Abbreviations ESKD: End-stage kidney disease GLP-1 RA: Glucagon-like peptide-1 receptor agonist HF: Heart failure ICER: Incremental cost-effectiveness ratio MI: Myocardial infarction NDSS: National Diabetes Services Scheme QALY: Quality-adjusted life year SGLT2i: Sodiumglucose co-transporter 2 inhibitor References McGuire DK, Shih WJ, Cosentino F et al (2021) Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with type 2 diabetes: a meta-analysis

By providing mice with simultaneous access to diets or solutions with different carbohydrate/simple sugar content we can determine whether GLP-1RA-mediated increases in FGF21 also affect dietary preferences

As a result, we eat less because we are thinking less about food, and we are satisfied with smaller portions even if we werent overeating
