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For a deeper comparison of treatment options, see our Semaglutide vs Tirzepatide guide How Do GLP-1 Medications Promote Weight Loss
In the same study, semaglutide decreased heart failure and all-cause mortality by 18% and 19% (respectively)
In addition, injectable semaglutide has greater weight reduction than oral semaglutide [73]
Because these studies allow for concomitant insulin adjustments, and they lack a controlled group (i.e., placebo) interpretation of the A1c reduction is very difficult
