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For patients with severe obesity (BMI 40 or 35 with obesity-related complications), referral for evaluation of bariatric surgery may be appropriate according to American Society for Metabolic and Bariatric Surgery guidelines

A GP can assess whether hormonal investigations are warranted for example, checking testosterone, oestrogen, thyroid function, or prolactin levels and can refer to an endocrinologist or sexual health specialist if appropriate

Breaks in semaglutide cold chain managementwhether due to logistical mishaps, improper storage at pharmacies, or mishandling by end-userspose significant risks to the efficacy of these therapies