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Description
Myocardial Metabolism The GLP-1 agonists increase myocardial glucose uptake and change the metabolic pathways toward glucose oxidation by increasing the energy efficiency of the heart during ischemia or failure [9]
Also used off-label for weight loss
In clinical trials for type 2 diabetes (SURPASS), nausea was reported by approximately 12-29% of patients receiving tirzepatide, depending on the dose, compared to 6-8% receiving placebo
Sutin et al., 2020)
