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Often, yes, GLP-1s may be safer for patients unfit for anesthesia or major surgery, though risks like nausea and long-term dependence remain.

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Injection timing within the week Retatrutide is administered once weekly, and the dose schedule recommends injecting on the same day each week

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EU product information explicitly warns that nausea, vomiting and diarrhoea may cause dehydration and advises precautions to avoid fluid depletion

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Per the Ridha 2024 Aesthetic Surgery Journal paper (PMID 38874170), the temporal fat pad is among the most affected compartments

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