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Originally developed for diabetes and weight loss, GLP-1 medications may help quiet the brains reward circuitry, muting the intense craving signals associated with Substance Use Disorders

I was prediabetic and had high cholesterol, but my recent blood work shows normal levels
Interestingly, appendicular BMD, but not axial BMD, was not reduced despite significant weight loss in the semaglutide group and no changes in BTMs or bone microarchitecture was encountered [70]

Some patients experience temporary plateaus lasting 12 weeks, which is normal and reflects your body's metabolic adjustment rather than treatment failure