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Some research suggests that the glucagon component may have muscle-sparing properties compared to pure GLP-1 agonists, but this requires further study

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Furthermore, GLP-1-based medications such as GLP-1 receptor agonists and dipeptidyl peptidase-4 inhibitors, have been shown to improve diabetes control in preclinical and clinical trials with human subjects

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Given the significant benefits associated with these medications, adverse side effects that lead to drug discontinuation warrant the consideration of a specialist consultation before withdrawal of treatment

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The letter did not cite manufacturing, safety, or medication quality problems

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