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This lessens the likelihood of eating past the point of fullness and/or comfort

When to Speak to Your GP About Feeling Cold on GLP-1 Treatment Whilst mild cold sensitivity is commonly reported during GLP-1 treatment and weight loss, certain symptoms warrant prompt medical review to exclude underlying pathology

Common contributors to gastroparesis include systemic and metabolic disorders, with prevalent factors being diabetes (25%), medications (22%), postsurgical reasons (7%), and additional factors such as Parkinsons disease, connective tissue disorders, and specific infections such as enteroviruses [2]

Who Should Not Use These Compounds and What Are the Key Risks Neither retatrutide nor tirzepatide is appropriate for individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2), based on preclinical signals observed across the GLP-1 receptor agonist class