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Cachexia is a significant loss of body weight, mainly from muscle mass, that induces a loss of physical function and cannot be reversed by conventional nutritional means (69)

Early and late-stage clinical trial coverage has reported major weight-loss results, and some discussions have focused on whether retatrutide may help support better body composition during weight loss

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Eligibility criteria may also differ between source plasma donation (plasmapheresis) and transfusion plasma donation contexts