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Description
This observed lack in the expression of the receptor may be related to the fact that it is necessary to trigger an inflammatory response in the brain to increase its density, which indicates that it plays a role in controlling inflammation [22,91]

The S-LiTE (Synergy effect of the appetite hormone GLP-1 [liraglutide] and Exercise on maintenance of weight loss and health after a low-calorie diet) trial provides perhaps the most rigorous test of additivity [6]

References World Health Organization
Modulation of insulin sensitivity by exercise training: implications for cardiovascular prevention
