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Janelle Jakobi, an obesity medicine specialist and bariatric physician assistant at Houston Methodist Willowbrook Hospital who routinely cares for patients using these medications, said the observational findings offer hopeful insight for those facing mental health struggles while utilizing weight loss medication

GLP-1 receptor agonists decrease toxic alcohol metabolites In the study, researchers observed that GLP-1 receptor agonists decreased levels of a liver enzyme known as Cyp2e1, which breaks down alcohol into a toxic metabolite called acetaldehyde

2025 Mar;31(3):951-962

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