glp 1 weight gain REPEATED GLP-1 USE MAY PROMOTE LONG TERM GAIN: A new mice study found exactly that. Repeated cycles of GLP-1's may have long term adverse effects on the very thing they were GLP-1R Agonists for Weight Loss
Description
However, recent research based on human clinical data is providing much more reassuring evidence about the safety profile of these medications

Furthermore, the secretome of hMSC-Ex-4 displayed an altered protein profile, including enhanced secretion of insulin-like growth factorbinding protein 2 (IGFBP2) and apolipoprotein M (APOM), both of which are implicated in metabolic regulation and may contribute to the therapeutic modulation of type 2 diabetes mellitus [18]

Effectiveness Semaglutide and Tirzepatide are effective in promoting weight loss, with studies showing Semaglutide users lose about 15% of their body weight and Tirzepatide users around 20% over a year

As a result, diabetes is now the leading cause of end-stage kidney disease in Western countries
