semaglutide severe side effects Comparative safety and of and tirzepatide: Implications for clinical decision-making in obesity management The Surprising Ozempic Side Effects
Description
Most patients go home the same day or the next
There was a treatment-related increase in serum amylase concentration (mean SD) from baseline to the end of semaglutide treatment of 1.5 15.3 U/L and to follow-up of 7.0 14.1 U/L

Additional experimental data support the protective role of GLP-1, including improved outcomes in DPP-4 knockout rats exposed to endotoxins and reduced mortality following GLP-1R activation (Ku et al., 2010)
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Based on the clinical trials leading to their approval, the rates of these side effects appear to be comparable for Ozempic and Wegovy
