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2008;478:136e42
Similarly, Lincoff et al59 conducted an RCT enrolling 17,604 patients aged 45 years or older with pre-existing cardiovascular disease and a BMI of 27 or higher but without a history of diabetes
For example, one of the most notable trials on the subject is the ELAD trial, which stands for Evaluating Liraglutide in Alzheimer's Disease. This 12-month RCT reported that liraglutide improves cognitive function and MRI volume in the temporal lobe and whole cortex, suggesting a potential benefit in treating Alzheimer's [21]
Medical history carries significant weight in candidacy determination
