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Deduced from both preclinical and human studies, GLP-1 has extra-pancreatic effects in the gut, kidney, nervous system, heart and immune system (Fig

While medication alone wont solve this global health crisis, GLP-1 therapies can help millions overcome obesity and reduce its associated harms. In the guidance, which was published in the journal JAMA , WHO makes two key recommendations
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Looking for the next step in obesity pharmacotherapies, the concept of combining entero-pancreatic hormones for obesity treatment was supported by the marked WL, sustained weight maintenance, and metabolic benefits observed with BS, which increase multiple gut hormone levels [914]
