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In the head-to-head comparison between tirzepatide and semaglutide, the two drugs yielded similar risks for component endpoints all-cause mortality (HR 1.03, 95% CI 0.84 to 1.27), myocardial infarction (HR 1.03, 95% CI 0.88 to 1.21) and stroke (HR 1.15, 95% CI 0.92 to 1.45) (Fig

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