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These effects are typically mild to moderate and tend to diminish over time with continued use

The Role of Dietary Acid Load on Progression of Estimated Glomerular Filtration Rate Among Individuals Diagnosed With Chronic Kidney Disease

That's especially true if you've tried to diet and exercise in the past, only to have your weight balloon back up after a couple months

Interleukin 6 (rs1800795) gene polymorphism is associated with cardiovascular diseases: A meta-analysis of 74 studies with 86,229 subjects
