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The subsequent downstream signaling cascade initiated from substrates of the insulin receptor activates kinases and transcription factors vital in promoting cell metabolism, neuronal growth and differentiation, gene transcription, synaptic plasticity, and neuroprotection [133] (Fig
Gudipally PR et al
The drug is to be used in combination with lifestyle changes to aid in weight loss
Here is what they found in the human patients: Fat-to-body-weight ratio significantly decreased
