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Similar reductions in serum LH were reported with GLP-1/GIP administration, while GLP-1/E treatment restored estrous cyclicity and increased the number of corpora lutea across multiple generations (Sanchez-Garrido et al., 2024)
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However, early on, it was noted that insulin derived from pancreatic extracts [1] or as crude insulin preparations [2] sometimes first elevated blood glucose and then later decreased blood glucose levels
Endocrinology 149 , 574579 (2008)
