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Pain Pain GLP-1s are also being investigated for osteoarthritis pain and disease progression

The SUSTAIN 6 trial demonstrated a 26% reduction in major adverse cardiovascular events in patients with type 2 diabetes

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The chronic low-grade inflammatory state that results, sometimes called inflammaging, creates a systemic environment that progressively impairs insulin sensitivity, disrupts lipid metabolism, and elevates cardiometabolic risk [4,5]
