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But that doesnt necessarily need to be the case, says Wood

According to American Diabetes Association guidelines, diabetes is diagnosed when A1C 6.5%, fasting plasma glucose 126 mg/dL, 2-hour plasma glucose 200 mg/dL during an oral glucose tolerance test, or random plasma glucose 200 mg/dL with classic symptoms

As such, there is a good rationale for leptin analogues in the treatment of obesity

For someone targeting 160 pounds, this means 128 to 160 grams daily
