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Rosiglitazone protects against palmitate-induced pancreatic beta-cell death by activation of autophagy via 5-AMP-activated protein kinase modulation

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MIN6 cells were pretreated with 1 mM metformin for 2 h (thin dotted line of left panel) or simultaneously with 10 nM GLP-1 (thick dotted line of left panel)

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Empty vectors were co-transfected into target cells to act as controls

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