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Among CagriSema-treated participants, 73.5% achieved HbA1c of 6.5% or below compared to 15.9% with placebo, demonstrating remarkable dual efficacy for both weight and glycemic endpoints

When medication potency decreases, patients with type 2 diabetes may experience inadequate glycemic control, with blood glucose levels rising above target ranges

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Endocrinology 150:17121722 Kerr BD, Flatt PR, Gault VA (2010) (D-nn2)Oxm[mPEG-PAL]: a novel chemically modified analogue of oxyntomodulin with antihyperglycaemic, insulinotropic and anorexigenic actions