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2.5 Anti-angiogenic effect Abnormal angiogenesis plays a significant role in the pathogenesis of several eye diseases, particularly those involving retinal ischemia and neovascularization

[DOI] [PMC free article] [PubMed] [Google Scholar] [19].Rogliani P, Calzetta L, Capuani B, et al

Claims about medication efficacy are based on clinical studies and may not apply to all individuals

On the other hand, the vasodilatory effects of GLP-1 RAs can also be mediated through amelioration of endothelial function, which in turn affects vascular smooth muscle tone through release of nitric oxide, endothelium-derived hyperpolarizing factor, and prostacyclins (Sandoo et al., 2010)