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In a case report on a person with exenatide-associated acute kidney injury, kidney biopsy showed active, moderately severe, diffuse tubulointerstitial nephritis with infiltration of eosinophils [150]

Comorbidity management may extend or shorten treatment duration

The risk for thyroid cancer over a maximum of 8 years of follow-up did not differ between GLP-1 medication users and adults using an SGLT2 inhibitor, DPP-IV inhibitor or sulfonylurea, though GLP-1 users did have a higher thyroid cancer risk during the first year of therapy

Additionally, 3041% of participants in the higher-dose groups discontinued at least one antihypertensive medication