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Description
Significance statement Acylation is a common strategy to enhance the pharmacokinetics of peptide-based drugs
GLP-1 receptor agonists work by mimicking this hormone

And for those who titrate up to higher doses , the constipation can return or worsen with each dose increase

The predominance of primary care prescribing suggests that the oral formulation may lower barriers to use outside of specialty care, aligning with its potential to broaden access to obesity treatment
