glp 1 cardiovascular effects and Tolerability of GLP-1 Receptor Agonists: A Systematic Review and Meta-Analysis of 99,599 Patients The Many Cardiovascular Benefits of
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(2009) [20] compares the pancreatitis risk of nearly 30,000 exenatide users and a similar number of matched comparators and finds no significant association between exenatide and pancreatitis
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While these findings provide preliminary evidence of the potential benefit of semaglutide in CUD in real-world populations further preclinical studies are warranted to understand the underlying mechanism and randomized clinical trials are needed to support its use clinically for CUD
