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Description
Combinacin de mecanismos metablicos que podran ofrecer ventajas en subgrupos de pacientes difciles de tratar

GLP-1R agonist exendin-4 protects against hemorrhagic transformation induced by rtPA after ischemic stroke via the Wnt/-catenin signaling pathway

In the brain, the two incretins are not redundant and may complement each other in regulating orexigenic and anorexigenic pathways (148)
Owing to the pain and loss of function induced by this disease, it reduces the quality of life and causes a considerable economic burden estimated at $350 billion in the United States alone 4
